Path 3 of 3
Beyond MTHFR
MTHFR is where most people start — but it's one instrument in a much larger orchestra. This is the deep end: the other genes that shape how your body handles folate, B12, stress chemistry, and detox — and what each one actually does.
MTHFR doesn't work alone: the genes worth checking alongside it
MTHFR is one step in a bigger cycle. Looking at it next to a handful of related genes tells a far more useful story than MTHFR by itself.
The COMT gene: stress, focus, estrogen — and why it's talked about with MTHFR
COMT (and its famous Val158Met / rs4680 variant) shapes how you clear stress chemicals and estrogen. A calm, plain-English guide to what it does and why it matters.
MTR and MTRR: the B12 side of methylation
MTHFR gets the spotlight, but MTR and MTRR are the genes that actually use your B12 to finish the job. A plain-English guide to the pair — and the A66G variant.